NCCT NWU (Net Water Uptake)

Stroke quantification where there is no perfusion scanner

NCCT NWU Insightz reads a routine non-contrast head CT and returns Net Water Uptake (NWU), a deep-learning infarct core, and an automated CT-ASPECTS score — bringing quantitative measurement to centres that have no CTP or MRI, for interpretation by qualified healthcare professionals.

NCCT NWU Insightz — NWU > 11.5% — NWU > 11.5%

NCCT NWU Insightz — DL core · NWU > 11.5% · Elevated NWU — DL core · NWU > 11.5% · Elevated NWU

NCCT NWU Insightz — Elevated NWU band — Elevated NWU band

What it measures

NWU is the percentage density loss of ischemic tissue against the mirrored healthy hemisphere — a direct imaging proxy for the water that accumulates in infarcted brain. The pipeline computes it voxel-wise, then reports it three ways: total core volume, an elevated band, and a mean within the DL-detected lesion.

How it works

Processing Pipeline

Fully automated from DICOM ingest to clinical report.

Pipeline

1Routine non-contrast head CT (DICOM) ingestion
2Density comparison against the mirrored healthy hemisphere
3Voxel-wise Net Water Uptake (NWU) computation
4Deep-learning lesion segmentation
5Automated CT-ASPECTS across all 10 regions
63-page structured report generation

Outputs

Voxel-wise NWU
DL infarct core (mL, left/right)
NWU > 11.5% volume (mL, left/right)
Elevated NWU band
CT-ASPECTS 0–10 with per-region table
Segmentation overlays on axial slices and in the viewer

Clinical output

Measurements

Net Water Uptake (NWU)

Percentage density loss against the mirrored healthy hemisphere, computed voxel-wise

DL Infarct Core

Deep-learning core volume in mL, left and right

NWU > 11.5% Volume

Core volume by NWU threshold in mL, left and right

Core Concordance

Agreement between the two independent core estimates

Mean Lesion NWU

Mean NWU within the DL-detected lesion

CT-ASPECTS

0–10, with involved/normal status for each of the 10 regions

Report

What the report gives the clinician (3 pages)

CT-ASPECTS 0–10 with a per-region involved/normal table across all 10 regions
Two independent core estimates — DL infarct core (mL, left/right) and NWU > 11.5% (mL, left/right) — plus their concordance, so disagreement is visible rather than hidden
Elevated NWU band with lateralised excess and a stated detection limit
Edema progression rate (%/h) when onset or last-known-well time is supplied — and onset can be entered after processing, re-rendering the report without re-running the scan
Literature-referenced flags for large core volume, hemispheric involvement, insula involvement and a published malignant-edema criterion, each carrying its citation
Segmentation overlays on axial slices, and the same overlays in the viewer

Sample output

AI-Generated Visualizations

A preview of the parameter maps and overlays generated by NCCT NWU Insightz. For the complete clinical report, .

Segmentation maps on axial slices — DL core (top), NWU > 11.5% (middle) and elevated NWU band (bottom)

Ready to experience NCCT NWU Insightz?

Schedule a personalized demo to see how our AI-powered perfusion analysis transforms your clinical workflow.